Research Projects

Scylla Biotech participates in national and European research programs focused on biotechnology, infectious diseases and molecular therapeutics.
The company collaborates with universities, research institutes and industrial partners to develop innovative biomedical solutions.

Below you can find information about recent and ongoing research projects.

FRAIR – Recombinant Antibody Fragments for RNA Therapeutics

Program: PNRR – National Center for Gene Therapy and RNA-based Drugs (CN00000041) – Spoke 6 "RNA Drug Development"
Partners: University of Messina – CNR network
Period: 2023–ongoing

Description:
The FRAIR project focuses on the isolation and characterization of recombinant antibody fragments capable of recognizing modified antisense oligonucleotides. These reagents are developed as tools for monitoring and studying RNA-based therapeutics and their biological activity.

Status: Ongoing

GENESIS – Intrahost Persistence of Emerging Arboviruses

Program: PNRR – One Health Basic and Translational Actions Addressing Unmet Needs on Emerging Infectious Diseases (INF-ACT)
Proponent: University of Pavia
Period: 2024–ongoing

Description:
The project investigates molecular and immunological mechanisms underlying the persistence of emerging arboviruses, including Zika virus. The research aims to identify new strategies for antiviral intervention and immune-based therapies.

Status: Ongoing

FLAME – FLAvivirus Molecular Mechanisms and Therapies

Program: PR FESR Sicilia 2021–2027 – Industrial Research and Experimental Development
Partner: University of Messina
Period: 2026–2027 ?

Description:
The project explores molecular mechanisms involved in flavivirus infections and investigates innovative strategies to modulate host immune responses and viral replication.

Status: Under evaluation 

CANCER-C8 – Caspase-8 Antagonism for Neutrophil-Enhanced Cancer Eradication

Program: PN RIC 2021–2027 – Strategic Research Supply Chains
Partner: Consiglio Nazionale delle Ricerche (CNR)
Period: 2026–2027 

Description:
The project investigates the role of Caspase-8 inhibition in enhancing innate immune responses mediated by neutrophils, with potential applications in both cancer therapy and infectious diseases.

Status: Approved

MARE / N-CITE Research Ecosystem

Program: PN RIC 2021–2027 – Research Ecosystems
Coordinator: Fondazione IN-FACT
Period: 2026–2027 

Description:
Participation in a national research ecosystem focused on the development of integrated platforms for monitoring and analysis of biological systems and infectious disease dynamics.

Status: Approved

Additional projects and collaborations are currently under development within national and European research programs.