Services
- Screening of hundreds of therapeutic antibodies for rapidly selecting the best candidates
- Precision information on the binding site of your antibodies
- Functional characterization of the epitope: identify the amino-acid residues required for antibody binding (these may include both antibody contact points and regions required for producing the "right" antigen conformation)
- Profiling of patients' sera for biomarker detection
- Profiling of vaccinees' sera for identification of the antigen regions targeted by the antibody response
- Epitope engineering to optimize structure-based vaccine development
- Selection of the best adjuvant to target the desired epitope
- Evaluation of protective effects of vaccine candidates, in in vivo and in vitro models
- Screening of B cell/plasmablast/hybridoma culture supernatants for finding clones with the desired epitope specificity in the early phases of monoclonal antibody production
- Quality control of vaccine batches